Bronxville Science Department: March 2018

One of the suggested AP Biology labs involved producing a mathematical model of the Hardy Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences.

The students produce a spreadsheet to follow the phenotype and gene frequencies that result when Hardy and Weinberg's equilibrium is held constant because their conditions are being met. (Large population, no natural selection, no mutations, no emigration/immigration, mating is random.)

In past years, student have been asked to violate one of those condition to see how it causes the model to change. This year, I asked them to research an actual genetic disease and alter the standard equation's parameters to see how modern medical practices or natural selection would affect the gene frequencies in theirr models.

Sarah G. examined Werner Syndrome. Model.

Werner Syndrome by Charles Ippolito on Scribd

Mairead C. examined Bipolar Disorder.

Bipolar Disorder by Charles Ippolito on Scribd

Amanda S. examined Blue/Yellow Colorblindness. Model.

Color Blindness by Charles Ippolito on Scribd

Olivia S. Examined Red/Green Color Blindness.

Color Blindness - Red and Green by Charles Ippolito on Scribd

Susie G. examined Aniridia. Model.

Anaridia by Charles Ippolito on Scribd

Nathan R. examined Alexander Disease. Model.

Alexander Disease by Charles Ippolito on Scribd

Isabella D. examined Diabetes.

Q3BIO Project by Charles Ippolito on Scribd

Kirsten I. examined Sickle Cell Anemia by designing a Informational Brochure that might be distrbuted to patients in a doctor's office. Model without medical intervention. Model with medical intervention.

Sickle Cell Anemia by Charles Ippolito on Scribd

Julia P. examined Anencephaly.

Anencephaly by Charles Ippolito on Scribd

Robert S. examined Schizophrenia.

SchizoPhrenia by Charles Ippolito on Scribd

Jack K. created a website examining Tyrosinemia. Model.

Hannah B. created a brochure describing Hemochromatosis.

Hemochromatosis 02282018 by Charles Ippolito on Scribd

Ava A. examined Huntington's Disease.

Ava Austi_ AP Bio 3rd Quarter Project by Charles Ippolito on Scribd

Rachael P. Examined Acute Porphyria.

Acute Porphyria by Charles Ippolito on Scribd

Peter B. examined Prognathism.